6. What is the difference between multimodal, multi-effector, and multigenic therapies?
Multimodal therapies, also called combination therapies, utilize more than one modality of treatment such as messenger RNA, RNAi, gene therapy, and/or cell therapy.
Multi-effector therapies utilize more than one gene effector to treat a disease, targeting complex disease states that require the action of more than one therapeutic effector on different nodes of the disease.
Multigenic therapies target complex diseases by using more than one transcript which encodes for two or more open reading frames and/or two or more bioactive RNA molecules.
You can make therapies that are multimodal, multi-effector, and multigenic, or you can make therapies that fall under just one or two of these categories.