Mouse IL-11

A cytokine that promotes the proliferation of hematopoietic stem cells and megakaryocyte progenitors, enhancing platelet production. It also stimulates hepatocyte proliferation in response to liver damage. IL-11 binds to a receptor complex formed by IL6ST and either IL11RA1 or IL11RA2, activating intracellular protein kinases and phosphorylating STAT3. This signaling promotes cell proliferation, particularly in cancer contexts. IL-11 can engage in 'classic signaling' with membrane-bound receptors or 'trans-signaling' when bound to soluble IL11RA.
License Type
Product number: SW10097.1

TU-1

hERP29 Proximal Promoter, a Synthetic Splice, and a portion of the hACTB gene.

A portion of the hUCP2 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hS100A11 gene.

A portion of the hEIF-4A1 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hADAM9 gene.

A portion of the hPCNA Proximal Promoter, a Synthetic Splice, and a terminal portion of the hCOL5A1 gene.

A portion of the Murine Cytohesin-1 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hACTN1 gene.

A portion of the Mus E2A Proximal Promoter, a Synthetic Splice, and a terminal portion of the hKDELR3 gene.

A portion of the hPNP Proximal Promoter, a Synthetic Splice, and a terminal portion of the hANPEP gene. 

A portion of the bMHC Proximal Promoter, a Synthetic Splice, and a terminal portion of the hCD58 gene

*NOTE: bMHC info (USPTO-US005441889A)

hERP29 Proximal Promoter, a Synthetic Splice, and a portion of the hACTB gene.

A portion of the hUCP2 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hS100A11 gene.

A portion of the hEIF-4A1 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hADAM9 gene.

A portion of the hPCNA Proximal Promoter, a Synthetic Splice, and a terminal portion of the hCOL5A1 gene.

A portion of the Murine Cytohesin-1 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hACTN1 gene.

A portion of the Mus E2A Proximal Promoter, a Synthetic Splice, and a terminal portion of the hKDELR3 gene.

A portion of the hPNP Proximal Promoter, a Synthetic Splice, and a terminal portion of the hANPEP gene. 

A portion of the bMHC Proximal Promoter, a Synthetic Splice, and a terminal portion of the hCD58 gene

*NOTE: bMHC info (USPTO-US005441889A)